Title:
Medical treatment of the insulin gene (INS) associated diseases by control of the natural antisense transcript to an insulin gene (INS)
Document Type and Number:
Japanese Patent JP6128848
Kind Code:
B2
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of an Insulin gene (INS), in particular, by targeting natural antisense polynucleotides of an Insulin gene (INS). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Insulin Gene (INS).
Inventors:
Joseph Colored
Olga Corkova Sherman
Olga Corkova Sherman
Application Number:
JP2012523947A
Publication Date:
May 17, 2017
Filing Date:
August 05, 2010
Export Citation:
Assignee:
Kuruna Incorporated
International Classes:
C12N15/09; A61K31/7088; A61K48/00; A61P3/04; A61P3/06; A61P3/10; A61P9/12; A61P13/08; A61P13/12; A61P15/08; A61P35/00; A61P37/06; C12N15/113; G16B30/10
Domestic Patent References:
| JP2005500002A |
Foreign References:
| US6110707 | ||||
| WO2009062113A1 |
Other References:
Pancreas,2005,Vol.31,No.4,p.373-379
Gene Expr.,2007,Vol.13,p.227-239
Gene Expr.,2007,Vol.13,p.227-239
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe