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Title:
MEDICINE FOR ARTICULAR RHEUMATISM
Document Type and Number:
Japanese Patent JP3507521
Kind Code:
B2
Abstract:

PURPOSE: To obtain a medicine for articular rheumatism, having an excellent anti-articular rheumatism effect, low in toxicity and capable of effectively exhibiting its effect by a small dose.
CONSTITUTION: This medicine for articular rheumatism is prepared by reacting gold or a gold compound with a nucleic acid (DNA and/or RNA) derived from a biological material and using the resultant gold-nucleic acid complex. A DNA or an RNA and gold or a gold compound are added to a prescribed buffer solution in a weight ratio of (DNA:gold) of (1:10) to (100:1) and allowed to react under stirring at 100 to 300°C in an autoclave with a stirrer. After completion of the reaction, the resultant gold-nucleic acid complex is separated and purified according to the liquid chromatography method, the dialysis method, etc.


Inventors:
Shuji Sakuma
Masanori Atsumi
Keijiro Fujita
Application Number:
JP5125593A
Publication Date:
March 15, 2004
Filing Date:
February 18, 1993
Export Citation:
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Assignee:
Sangi Co., Ltd.
International Classes:
A61K31/28; A61K31/70; A61K31/7135; A61K33/24; A61P29/00; C07H23/00; (IPC1-7): A61K31/70; A61K31/28; A61K33/24; A61P29/00
Domestic Patent References:
JP4187638A
JP2502547A
Attorney, Agent or Firm:
Hideaki Kuwahara