Title:
膵臓癌の治療のためのゲムシタビンと併用した中鎖脂肪酸、その塩およびトリグリセリド
Document Type and Number:
Japanese Patent JP5473937
Kind Code:
B2
Abstract:
The present invention relates to the use of medium-chain length fatty acids of formula I, triglycerides of formula 2 (wherein n=6-10), salts thereof, or mixtures thereof, in combination with gemcitabine and optionally erlotinib in the treatment of pancreatic cancer in human patients. Exemplary medium-chain length fatty acid/triglyceride compounds include capric acid, sodium caprate, tricaprin, lauric acid, sodium laurate, and trilaurin.
Inventors:
Lynn Ganion
Lilian gears
Christopher Penny
Lilian gears
Christopher Penny
Application Number:
JP2010538291A
Publication Date:
April 16, 2014
Filing Date:
December 18, 2008
Export Citation:
Assignee:
ProMetic BioSciences Inc.
International Classes:
A61K31/20; A61K31/23; A61K31/517; A61K31/7068; A61P35/00; A61P43/00
Domestic Patent References:
| JP4504562A |
Foreign References:
| WO2006120120A1 | ||||
| WO2004069237A1 | ||||
| WO2003020210A1 | ||||
| WO2002083120A1 | ||||
| WO2001017517A1 |
Other References:
J.Hering, et al., Annals of Surgical Oncology, Sep.2007, 14(12), pp3620-3628
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Sakurai Yoko
Takuji Yamada
Michiko Matsutani
Sakurai Yoko