Title:
METABOLITE OF ECTEINASCIDIN 743
Document Type and Number:
Japanese Patent JP2010215656
Kind Code:
A
Abstract:
To provide related structures having the same or higher level antitumor activities than conspicuous antitumor activities of the ecteinascidin (Et) 743 compound.
Compounds having structural formula of the figure have the same or higher level antitumor activities than those of the Et 743.
Inventors:
RINEHART KENNETH L
MORALES JOSE J
REID JOEL
REYMUNDO ISABEL
FLORIANO PABLO
GARCIA GRAVALOS LOLA
MORALES JOSE J
REID JOEL
REYMUNDO ISABEL
FLORIANO PABLO
GARCIA GRAVALOS LOLA
Application Number:
JP2010131960A
Publication Date:
September 30, 2010
Filing Date:
June 09, 2010
Export Citation:
Assignee:
PHARMA MAR SA
International Classes:
C07D317/64; A61K31/357; A61K31/36; A61K31/39; A61K31/47; A61K31/472; A61K31/4747; A61K31/4995; A61K35/02; A61P35/00; A61P35/02; C07D217/10; C07D217/24; C07D317/44; C07D317/66; C07D327/02; C07D411/14; C07D491/14; C07D497/22; C07D515/22; C12Q1/26
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro