Title:
HMG-CoA還元阻害剤の製造のためのキラル中間体の製造方法
Document Type and Number:
Japanese Patent JP2011520876
Kind Code:
A
Abstract:
The present invention relates to a method for the commercial mass production of t-butyl (2,2-dimethyl-6-hydroxymethyl-[1,3]dioxane-4-yl) acetate having an optical activity, which is a core intermediate in the preparation of a variety of HMG-CoA reductase inhibitors, and to novel intermediates for the same. According to the preparation method of the present invention, t-butyl (2,2-dimethyl-6-hydroxymethyl-[1,3]dioxane-4-yl) acetate having an optical activity can be prepared in an economically advantageous and effective manner.
Inventors:
Lim Chun Woo
Park Young Mok
Jun Honi
Park Young Mok
Jun Honi
Application Number:
JP2011509418A
Publication Date:
July 21, 2011
Filing Date:
May 14, 2009
Export Citation:
Assignee:
WELL E&C CO., LTD.
International Classes:
C07D319/06; A61P3/06; A61P43/00; C07D209/24; C07D215/14; C07D239/42; C07D307/33; A61K31/404; A61K31/47; A61K31/505
Attorney, Agent or Firm:
Kenji Sugimura
Kazuyuki Tomita
Kengo Yoshida
Kazuyuki Tomita
Kengo Yoshida