Title:
Ｎ−アルキル基を含有するジュウテリウム化化合物の製造方法
Document Type and Number:
Japanese Patent JP5925301
Kind Code:
B2
Abstract:
The present invention relates to a process for deuteration of amines in the alpha and/or beta position of the N-atom by using a deuterium source and a Ruthenium(II) based catalyst.
Inventors:
Jens Atzroth
Volker Deldau
Wolfgang Hora
Matthias Beller
Lorenz Neubert
Dirk Michael
Volker Deldau
Wolfgang Hora
Matthias Beller
Lorenz Neubert
Dirk Michael
Application Number:
JP2014511830A
Publication Date:
May 25, 2016
Filing Date:
May 21, 2012
Export Citation:
Assignee:
SANOFI
International Classes:
C07B59/00; C07C209/68; C07C211/03; C07C211/07; C07C211/27; C07C211/48; C07C213/08; C07C215/30; C07C217/28; C07C231/12; C07C237/04; C07C237/34; C07D207/08; C07D211/22; C07D277/42; C07D295/02; C07D295/08; C07D333/66; C07D401/04; C07D403/06
Foreign References:
| US20100143287 | ||||
| WO2009005069A1 | ||||
| WO2008122010A1 | ||||
| US5167948 | ||||
| US5075337 | ||||
| WO2005070853A1 | ||||
| WO2004060831A1 | ||||
| US5846514 |
Other References:
Journal of Labelled Compounds and Radiopharmaceuticals,2010年,53,p.704-715
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi