Title:
光学活性1-アルキル置換-2,2,2-トリフルオロエチルアミンの製造方法
Document Type and Number:
Japanese Patent JP4287703
Kind Code:
B2
Abstract:
The present invention relates to a process for producing an optically active 1-alkyl-substituted 2,2,2-trifluoroethylamine, which is an important intermediate of medicines and agricultural chemicals, and which is represented by the formula [3] [in the formula R represents a lower alkyl group of a carbon and * represents an asymmetric carbon], or its salt by subjecting an optically active imine represented by the formula [1] to an asymmetric reduction under hydrogen atmosphere using a metal catalyst of Group VIII to convert it into an optically active secondary amine represented by the formula [2] and then by subjecting the secondary amine or its salt to hydrogenolysis.
Inventors:
Akio Ishii
Kuriyama Katsu
Yasumoto Manabu
Masai Kanai
Inomiya Kento
Takafumi Otsuka
Koji Ueda
Kuriyama Katsu
Yasumoto Manabu
Masai Kanai
Inomiya Kento
Takafumi Otsuka
Koji Ueda
Application Number:
JP2003166525A
Publication Date:
July 01, 2009
Filing Date:
June 11, 2003
Export Citation:
Assignee:
Central Glass Co., Ltd.
International Classes:
C07C209/52; C07B53/00; C07B61/00; C07C209/62; C07C211/15; C07C249/02; C07C251/08
Domestic Patent References:
| JP2002173472A | ||||
| JP2002187873A |
Foreign References:
| US6166259 |
Attorney, Agent or Firm:
Yoshiaki Hanada