METHOD AND APPARATUS FOR CUTANEOUS ABSORPTION ENHANCEMENT AND PERCUTANEOUS DRUG DELIVERY

Japanese Patent JP2005296629

A

To provide an apparatus and a method for cutaneous absorption enhancement of drugs by applying electrical pulses.

A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: (i) bursts of electrical pulses to the skin surface, and (ii) vibrations to the skin surface. The vibrations are applied to the skin surface at a substantially same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.

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BERNABEI GIAN FRANCO

JP2005047835A

October 27, 2005

February 23, 2005

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MATTIOLI ENG LTD

A61M35/00; A61H9/00; A61H23/02; A61H39/00; A61N1/30; A61N1/32; A61M37/00; A61N7/00; (IPC1-7): A61M35/00

Shohei Oguri
Hironori Honda
Toshimitsu Ichikawa
Takeshi Takamatsu
Yuriko Hamada

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