To provide a method and an apparatus for cryoprecipitation and chromatography.
A method and a system 10 for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels 20. Ultrasonic energy from ultrasonic drivers 42 is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated product. The ultrasonic energy prevents the growth of dendrite on the crystals to remove small crystals of the component to be removed without damage to or removal of the remaining components.
JPS61268301A | 1986-11-27 |
Toshio Shirane
Sadao Muramatsu