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Title:
METHOD OF CELL THERAPY FOR TREATMENT OF TUMOR
Document Type and Number:
Japanese Patent JP2010235611
Kind Code:
A
Abstract:

To provide a method of cell therapy for the treatment of tumor, especially the treatment of metastatic melanoma.

This method of cell therapy of a test subject comprises: steps of administration of an effective amount of interferon-α enhancing the expression of a tumor antigen on the surface of tumor to the test subject accompanying melanoma; and inoculation of an effective amount of own cytotoxic T lymphocyte having specificity to the melanoma-related target antigen to the test subject. A method of obtaining the cytotoxic T lymphocyte is also disclosed.


Inventors:
LETURCQ DIDIER J
MORIARTY ANN M
JACKSON MICHAEL R
PETERSON PER A
RICHARDS JON M
Application Number:
JP2010108798A
Publication Date:
October 21, 2010
Filing Date:
May 10, 2010
Export Citation:
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Assignee:
ORTHO MCNEIL PHARMACEUT INC
International Classes:
A61K35/14; A61K35/17; A61K38/21; A61P35/00; A61P43/00; C07K7/06
Domestic Patent References:
JPH11512433A1999-10-26
Foreign References:
WO2002065992A22002-08-29
Attorney, Agent or Firm:
Patent business corporation Odashima patent office