Title:
METHOD AND COMPOSITION FOR SPECIFIC COAGULATION OF VASCULATURE
Document Type and Number:
Japanese Patent JP2007016033
Kind Code:
A
Abstract:
To provide various compositions and methods for use in achieving specific coagulation, for example, coagulation of intratumoral vasculature and for use in overcoming the limitations of prior arts and in achieving specific blood coagulation by providing a new composition and a method having limited side effects.
This invention relates to a ligand comprising following (a) and (b): (a) a first binding region that binds to a component of diseased cells or disease-related vasculatures, or a component of disease-related stroma; the first binding region operatively linked to (b) a coagulation factor or a second binding region that binds to a coagulation factor.
Inventors:
THORPE PHILIP E
EDGINGTON THOMAS S
EDGINGTON THOMAS S
Application Number:
JP2006200132A
Publication Date:
January 25, 2007
Filing Date:
July 21, 2006
Export Citation:
Assignee:
UNIV TEXAS
SCRIPPS RESEARCH INST
SCRIPPS RESEARCH INST
International Classes:
C07K14/47; C12N15/09; A61K39/395; A61K47/48; A61P9/10; A61P13/08; A61P17/06; A61P19/02; A61P27/02; A61P27/06; A61P35/00; C07K14/82; C07K16/18; C07K16/22; C07K16/28; C07K16/30; C07K19/00; A61K38/00; A61P7/04; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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