Title:
細胞外小胞の検出方法
Document Type and Number:
Japanese Patent JP7226538
Kind Code:
B2
Abstract:
The present invention provides a method for quantifying a plurality of surface antigens simultaneously, thereby identifying an extracellular vesicle such as an exosome, and detecting and quantifying any surface antigen. Specifically, the present invention provides a method for detecting an extracellular vesicle, the method including: a step of labeling an extracellular vesicle in a sample using a first metal labeling reagent for labeling a nucleic acid and a second metal labeling reagent for labeling an extracellular vesicle surface antigen; and a step of identifying the first and second metal labeling reagents by mass spectrometry.
Inventors:
Makoto Watanabe
Hirotaka Fujimoto
Takaaki Sato
Hirotaka Fujimoto
Takaaki Sato
Application Number:
JP2021520733A
Publication Date:
February 21, 2023
Filing Date:
May 13, 2020
Export Citation:
Assignee:
SHIMADZU CORPORATION
International Classes:
G01N27/62; C12Q1/04; G01N33/53
Domestic Patent References:
| JP2017512985A |
Foreign References:
| WO2007140571A1 | ||||
| WO2018079689A1 | ||||
| WO2015068772A1 | ||||
| US20080193930 |
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office
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