Title:
胃癌由来の転移癌細胞の検出方法
Document Type and Number:
Japanese Patent JP4330372
Kind Code:
B2
Abstract:
Metastatic cancer cells originating from gastric cancer are detected by a method comprising the step of collecting a biological sample from a subject, the step of detecting the presence of at least either aldehyde dehydrogenase or dopa decarboxylase in the biological sample of the subject, and the step of determining that the possibility of containing metastatic cancer cells originating from the gastric cancer in the sample is high when at least either aldehyde dehydrogenase or dopa decarboxylase is present. By the use of these as markers for metastatic cancer cells originating from gastric cancer, the presence or absence of peritoneal metastasis in a gastric cancer patient can be detected rapidly and reliably, and data important for deciding whether intraperitoneal cancer chemotherapy should be applied is provided.
Inventors:
Yoshihide Hayashizaki
Yasushi Okazaki
Chohei Sakakura
Hisaichi Yamagishi
Yasushi Okazaki
Chohei Sakakura
Hisaichi Yamagishi
Application Number:
JP2003121780A
Publication Date:
September 16, 2009
Filing Date:
April 25, 2003
Export Citation:
Assignee:
RIKEN
International Classes:
C12Q1/02; G01N33/53; C12N15/09; C12Q1/32; C12Q1/527; C12Q1/68; G01N33/566; G01N33/573; G01N33/574
Other References:
癌と化学療法,2002, Vol.29, No.12, pp.2271-2274
日本癌学会総会記事,2001, Vol.60, p.528, #1817
日本癌学会総会記事,2002, Vol.61, p.335, #2267
日本癌治療学会誌,2002, Vol.37, No.2, p.539, PO37-3, PO37-4
Carcinogenesis,2001, Vol.22, No.3, pp.433-439
GI Research,2000, Vol.8, No.1, pp.56-61
Cancer Research,2001, Vol.61, pp.889-895
日本癌学会総会記事,2001, Vol.60, p.528, #1817
日本癌学会総会記事,2002, Vol.61, p.335, #2267
日本癌治療学会誌,2002, Vol.37, No.2, p.539, PO37-3, PO37-4
Carcinogenesis,2001, Vol.22, No.3, pp.433-439
GI Research,2000, Vol.8, No.1, pp.56-61
Cancer Research,2001, Vol.61, pp.889-895
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo