Title:
METHOD FOR DETECTING POLYNUCLEOTIDE
Document Type and Number:
Japanese Patent JP3188303
Kind Code:
B2
Abstract:
PURPOSE: To determine polynucleotide in high sensitivity and in high precision by associating different sites of polynucleotide chain with two or more mutually complementary labeled probes and measuring the number of formed complexes.
CONSTITUTION: A polynucleotide as a substance to be measured is associated with two or more mutually complementary label probes at different sites of the polynucleotide. The number of complexes of the label probe and the substance to be measured is distinguished as existence of each molecule of the label probe and measured. Labeling of radioisotope is not required.
Inventors:
Kazunobu Okano
Satoshi Takahashi
Hideki Kanbara
Keiichi Nagai
Satoshi Takahashi
Hideki Kanbara
Keiichi Nagai
Application Number:
JP9126592A
Publication Date:
July 16, 2001
Filing Date:
April 10, 1992
Export Citation:
Assignee:
株式会社日立製作所
International Classes:
C12Q1/68; C12N15/09; G01N21/64; G01N21/78; G01N33/58; (IPC1-7): C12Q1/68; G01N21/78; G01N33/58
Domestic Patent References:
| JP61191964A | ||||
| JP2268700A | ||||
| JP3280900A | ||||
| JP2295496A | ||||
| JP6273138A | ||||
| JP643541A | ||||
| JP62106347A | ||||
| JP2153100A |
Attorney, Agent or Firm:
Yuusuke Hiraki
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