Title:
METHOD AND DEVICE FOR CALCULATING OPTIMUM SOLUTION OF MULTIPLEX VARIATION PROTEIN AMINO ACID ARRAY AND STORAGE MEDIUM STORING PROGRAM FOR CONDUCTING THE SAME
Document Type and Number:
Japanese Patent JP3964087
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To select an optimum solution based on a feature value in short time without deteriorating precision from a multiplex variation protein group whose number of combinations is huge.
SOLUTION: A method for calculating the optimum solution of a multiplex variation protein amino acid array includes a step for calculating the optimum stereoscopic structure coordinate of multiplex variation protein by searching the amino acid side chain stereoscopic structure coordinate of the respective amino acid arrays in a member by using a dead end elimination algorithm based on stereoscopic structure data of a model protein group with respect to the member of the multiplex variation protein group and by conducting the structure energy minimizing calculation of the member, a step for calculating the feature value from the optimum stereoscopic structure coordinate of optimum multiplex variation protein and a step for calculating the member optimizing the feature value by applying genetic algorithm to the multiplex variation protein group.
Inventors:
Morikawa Soichi
Nakai Takahisa
Kiyoto Ishii
Nakai Takahisa
Kiyoto Ishii
Application Number:
JP36849899A
Publication Date:
August 22, 2007
Filing Date:
December 24, 1999
Export Citation:
Assignee:
Kaneka Corporation
International Classes:
C12N15/09; G06F17/50; G16B15/20; C07K14/00; G06F17/30; G06F19/00; G16B20/00; G16B20/50; (IPC1-7): G06F17/50; C07K14/00; C12N15/09; //G06F17/00; G06F17/30
Domestic Patent References:
| JP8512159A |
Foreign References:
| WO1998047089A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto