To provide a method for easily and precisely evaluating a medicament deglutition disorder in an animal experiment because the evaluation of the medicament deglutition disorder in the animal experiment is highly expected as a profitable means for relieving the deglutition disorder with a medicament in the clinical operation on the site.
The method is for evaluating a medicament deglutition disorder in an animal experiment in the waking state, and comprises (1) a first process of recording an X-ray fluoroscopic image as an animation image in the state when the deglutition reaction is induced by dosing a contrast into the pharynx of an animal while X rays are continuously applied both to the pharynx and upper esophagus of the animal in the waking state previously medicated with a test medicine, lying on the side, from a side surface of the neck region, by using an X-ray fluoroscopic apparatus; and (2) a second process of evaluating the deglutition disorder of the contrast by analyzing the recorded image.
Toru Nakayama
Masayuki Enomoto