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Title:
METHOD FOR EVALUATING STRESS, STRESS-EVALUATION MARKER, METHOD FOR CREATING STRESSED MODEL ANIMAL, AND STRESSED MODEL ANIMAL
Document Type and Number:
Japanese Patent JP2013110969
Kind Code:
A
Abstract:

To provide a new method for evaluating stress by determining the expression level of a specific gene in a leukocyte.

The method for evaluating the stress uses at least one kind selected from the group consisting of Retn1g, Csta, Il1b, Camp, Tspan8, Mmp9, Add2, Eraf, Aqp1, Alas2, Hbb and the like as a stress-evaluation marker gene the expression level of which is used as an index. The method for creating the stressed model animal includes carrying out the breeding of a rat or a mouse in a wire net cage after carrying out the breeding thereof in a floored condition.


Inventors:
UEHARA MASAYUKI
Application Number:
JP2011257005A
Publication Date:
June 10, 2013
Filing Date:
November 25, 2011
Export Citation:
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Assignee:
SEIKO EPSON CORP
International Classes:
C12N15/09; A01K67/027; C12Q1/68; G01N33/50
Domestic Patent References:
JP2011004693A2011-01-13
JP2010187547A2010-09-02
JP2008253190A2008-10-23
Foreign References:
WO2008029838A12008-03-13
Other References:
JPN6015050022; Neuroscience Letters Vol.486, 2010, p.211-214
JPN6015050023; 日衛誌 Vol.52, 1998, p.647-653
JPN6015050024; 実験動物と環境 Vol.18, No.1, 2010, p.50-59
JPN6015050025; Biol. Psychiatry Vol.64, 2009, p.80S
JPN6015050026; Biochemical and Biophysical Research Communications Vol.314, 2004, p.356-362
JPN6015050027; Genomics Vol.81, 2003, p.588-595
Attorney, Agent or Firm:
Yoshiyuki Inaba
Katsuro Tanaka