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Patent Searching and Data


Title:
METHOD FOR FLUORESCENTLY LABELING PROTEIN
Document Type and Number:
Japanese Patent JP2010119382
Kind Code:
A
Abstract:

To provide a method for fluorescently labeling a protein labeling in vivo molecules.

The method for fluorescently labeling the protein includes to obtain a fused protein of a target protein with a variant -lactamase and to fluorescently label the target protein by bringing the fused protein into contact with a compound expressed by formula (I). In the formula (I), X represents a fluorescent group; Y represents a quenching group; L1 represents a linker for X; L2 represents a linker for Y; R1 represents H, a lower alkylene group or a lower alkyl group substituted with a lower alkylcarbonyloxy.


Inventors:
MIZUKAMI SUSUMU
KIKUCHI KAZUYA
WATANABE SHUJI
YAMAMOTO HIROSHI
Application Number:
JP2009195535A
Publication Date:
June 03, 2010
Filing Date:
August 26, 2009
Export Citation:
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Assignee:
UNIV OSAKA
International Classes:
C12N15/09; A61K49/00; C07D499/21; C07D501/60; C12Q1/34; G01N33/533; G01N33/58; C07K19/00
Attorney, Agent or Firm:
Ikeuchi, Sato & Partners