Title:
サイトカインを調節する作用物質の同定方法
Document Type and Number:
Japanese Patent JP2007527513
Kind Code:
A
Abstract:
The present invention relates to methods for identifying agents that modulate the effect of cytokine class I receptor binding compounds, by inhibiting the interaction between the cytokine class I receptor and nuclear factors. The agents are useful for decreasing IGF-1 levels in a cell, and for the treatment of medical disorders caused by hormone dysregulation, such as growth hormone or prolactin dysregulation.
Inventors:
Vendela Parov
Lotta Moreus
Lotta Moreus
Application Number:
JP2006518583A
Publication Date:
September 27, 2007
Filing Date:
June 28, 2004
Export Citation:
Assignee:
Biovitrum AB
International Classes:
G01N33/50; A61K45/00; A61P43/00; C07K16/28; C12N15/09; C12N15/18; C12Q1/02; C12Q1/68; G01N27/447; G01N33/15; G01N33/68; G01N33/74
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Tadayuki Motoyama
Kenji Tomita