To provide a method for implanting encapsulated cells into a host.
This invention relates to the method for implanting the encapsulated cells into the host, comprising exposing the cells to restrictive conditions for a sufficient period of time to establish a desired cell property in response to the restrictive conditions and implanting the encapsulated cells into the host, wherein, the cell property is substantially maintained following implantation. The encapsulated cells produce biologically active molecules. The molecules are useful for prevention or treatment of diseases or disorders, or useful in providing a metabolic function to, repairing or enhancement of the host. The cells produced in the method are useful in application in vitro, for diagnosis or other purposes. Also provided are cells produced by exposure to the restrictive conditions.
DIONNE KEITH E
HAMMANG JOSEPH P
RUDNICK SETH A
LYSAGHT MICHAEL J
Takaaki Yasumura
Natsuki Morishita