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Title:
外来物質の細胞内への導入方法ならびに該方法に用いる材料
Document Type and Number:
Japanese Patent JP6948660
Kind Code:
B2
Abstract:
Provided is a novel material used to introduce an exogenous substance into cells. Also provided is a method for introducing an exogenous substance into target cells using this material. The present invention provides an exosome that is used to introduce an exogenous substance into target cells, wherein the exosome contains one type or two or more types of an exogenous substance and a substance that induces macropinocytosis in the target cells. The present invention also provides a composition containing the exosome and a method for introducing an exogenous substance into cells using this exosome.

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Inventors:
Ikuhiko Nakase
Toru Yoshida
Bailey Kobayashi Naoko
Application Number:
JP2016559084A
Publication Date:
October 13, 2021
Filing Date:
November 11, 2015
Export Citation:
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Assignee:
Toagosei Co., Ltd.
Public University Corporation Osaka
International Classes:
C12N5/07; A61K9/10; A61K38/02; A61K45/00; A61K47/42; A61K47/46; A61P35/00; A61P43/00
Foreign References:
WO2011109677A1
Other References:
Mol Ther,2013,Vol.21,No.1,p185-191
Chem Biol,2012,Vol.19,No.11,p1437-1446
Human Gene Therapy,2011,Vol.22,p1463-1473
Attorney, Agent or Firm:
Makoto Abe



 
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