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Title:
METHOD OF INTRODUCING GRAFT CHAIN, POROSITY ADSORPTION FILM, AND PURIFICATION METHOD OF PROTEIN
Document Type and Number:
Japanese Patent JP2012224729
Kind Code:
A
Abstract:

To solve a problem that it is necessary to suppress the radical polymerization of monomers that is a competitive reaction when a graft chain suitable as an adsorption film is formed to a porous film.

The method which introduces a graft chain to a porous substrate including a polymer, includes: an immersion step in which the porous substrate is immersed in a solution including a radically polymerizable monomer; and an irradiation grafting step in which the porous substrate is irradiated in an immersed state, the radically polymerizable monomer is performed with graft polymerization to the porous substrate, and the graft chain is formed to the porous substrate, wherein the solution including the radically polymerizable monomer includes a solvent containing 40-70 vol% of a primary or secondary univalent lower alcohol.


Inventors:
YOKOYAMA TAKAO
SHIRATAKI HIRONOBU
Application Number:
JP2011092802A
Publication Date:
November 15, 2012
Filing Date:
April 19, 2011
Export Citation:
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Assignee:
ASAHI KASEI MEDICAL CO LTD
International Classes:
B01J20/26; C08J9/36; C08F2/46; C08F283/00; D06M14/30; D06M15/273; C07K1/14; C08F2/00; D06M101/30
Domestic Patent References:
JP2010158624A2010-07-22
JP2004209423A2004-07-29
JPH02187136A1990-07-23
Foreign References:
WO2009054226A12009-04-30
WO2011001963A12011-01-06
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito