To allow certain maintenance of a liquid medicine such as an insulin put in a pen type syringe at room temperature, and allowing easy achievement by only storing the pen type syringe in a thermos bottle marketed or present at home.

A pen type syringe has an outside diameter capable of being inserted into a cylindrical portable thermos bottle, a buffer cylinder having a cylindrical hole in which a liquid medicine side of the pen type syringe is positioned in the center of a holder is produced of a foamed resin, and the pen type syringe is inserted into the portable thermos bottle, so that the pen type syringe is not damaged by colliding with a hard inner wall of the thermos bottle, and an insulin thereinside is cold-insulated because a space is cooled by a cold insulator. Because disposing the cold insulator in the outer circumference of a heat insulation cylinder having a cylindrical hole into which an injection button side of the pen type syringe is inserted, the problem in which the pen type syringe directly contacts with the cold insulator to excessively cool the pen type syringe.