Title:
THREE-DIMENSIONAL MICROENVIRONMENTAL STRUCTURE FOR CELL BEHAVIOR REGULATION, THREE-DIMENSIONAL SURFACE FOR CELL BEHAVIOR REGULATION, ARRAYS, AND METHOD FOR MANUFACTURING THREE-DIMENSIONAL MICROENVIRONMENTAL STRUCTURE
Document Type and Number:
Japanese Patent JP2022081639
Kind Code:
A
Abstract:
To provide: three-dimensional microenvironmental structures that can accurately regulate cell behavior such as cell attachment, migration, growth, and differentiation; surfaces for cell behavior regulation; arrays; and methods for manufacturing three-dimensional microenvironmental structures.SOLUTION: Provided is a three-dimensional microenvironmental structure for cell behavior regulation, comprising a nanofiber membrane and two or more peptide motifs of P1 (first peptide) and P2 (second peptide), the P1 and P2 peptide motifs binding to two or more different receptors on a cell to generate a signal that controls the behavior of the cell, the P1 motif comprising a motif that binds to integrin α5β1, and the P2 motif, as a motif that binds to the co-receptor of the integrin α5β1, controlling the activity of the co-receptor of the integrin α5β1 to generate a signal that controls the cell behavior.SELECTED DRAWING: None
More Like This:
Inventors:
KIM CHAN
BAEK KYU-WON
GOO HUI-GWAN
LEE SANG-JAE
HONG BONG JIN
KOO SONG-HEE
SEO IN-YONG
LEE SEUNG-HOON
LEE JI-HYUN
JANG SEON-HO
SEO DONG-SIK
BAEK KYU-WON
GOO HUI-GWAN
LEE SANG-JAE
HONG BONG JIN
KOO SONG-HEE
SEO IN-YONG
LEE SEUNG-HOON
LEE JI-HYUN
JANG SEON-HO
SEO DONG-SIK
Application Number:
JP2022041936A
Publication Date:
May 31, 2022
Filing Date:
March 16, 2022
Export Citation:
Assignee:
AMOLIFESCIENCE CO LTD
KOLLODIS BIOSCIENCES INC
KOLLODIS BIOSCIENCES INC
International Classes:
C12M3/00
Domestic Patent References:
| JP2015528493A | 2015-09-28 | |||
| JP2007510820A | 2007-04-26 | |||
| JP2010207228A | 2010-09-24 | |||
| JP2009532070A | 2009-09-10 |
Foreign References:
| WO2014034146A1 | 2014-03-06 |
Attorney, Agent or Firm:
Patent Business Corporation Shinei Patent Office