Title:
遅延放出製剤を製造する方法
Document Type and Number:
Japanese Patent JP7391966
Kind Code:
B2
Abstract:
A method of producing a coatable core for a delayed release drug formulation for oral administration to deliver a drug to the colon. The method comprises forming a core comprising a drug. An outer layer coating preparation is formed by combining a first aqueous preparation of an enzymatically degradable polymer which is degradable by colonic bacterial enzymes; a second aqueous preparation of a film-forming enteric polymer having a pH threshold of about pH 6 or above; and an organic anti-tack agent. The core is then coated with the outer layer coating preparation to form an outer layer coated core.
Inventors:
Felipe, Balm
Leticia, von, Roccho
Karl Marx, Marx, Filler
Roberto, Carlos, Bravo, Gonzalez
Leticia, von, Roccho
Karl Marx, Marx, Filler
Roberto, Carlos, Bravo, Gonzalez
Application Number:
JP2021532824A
Publication Date:
December 05, 2023
Filing Date:
December 05, 2019
Export Citation:
Assignee:
TILLOTTS PHARMA AG
International Classes:
A61K9/36; A61K9/32; A61K9/48; A61K31/606; A61K45/00; A61K47/12; A61K47/14; A61K47/32; A61K47/36; A61P1/04
Domestic Patent References:
| JP2015515964A | ||||
| JP2019518758A |
Foreign References:
| WO2017138877A1 | ||||
| WO2019032027A1 |
Attorney, Agent or Firm:
Yukitaka Nakamura
Manabu Miyajima
Mari Asano
Hiroshi Sorimachi
Keiyasu Suzuki
Manabu Miyajima
Mari Asano
Hiroshi Sorimachi
Keiyasu Suzuki
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