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Title:
メトホルミンの製造方法
Document Type and Number:
Japanese Patent JP7447005
Kind Code:
B2
Abstract:
The present invention relates to an improved process for the preparation of metformin hydrochloride, an important drug in the first line treatment of Type II Diabetes.

Inventors:
Correia Camille
poly renault
Gerbaud Serge
Dittmann Marc
Mayard David
Hertner Sebastian
Application Number:
JP2020542432A
Publication Date:
March 11, 2024
Filing Date:
February 05, 2019
Export Citation:
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Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07C277/08; C07C279/26
Foreign References:
CN103435518A
CN104119250A
WO2016059507A1
Other References:
インド特許出願公開201621016063号明細書
FANG, W., et al.,Synthesis of Metformine Hydrochloride by Melting Method,Chinese Journal of Synthesis Chemistry,2008年10月,Vol. 16, No. 5,pp. 617-618
XU, T., et al.,Synthesis of Developer Metfomine Hydrochloride,Chemical Industry Times,2010年09月09日,Vol. 24, No. 9,pp. 17-19
Attorney, Agent or Firm:
Shinichiro Tanaka
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori