Title:
METHOD FOR MODULATING INFLAMMASOME ACTIVITY AND INFLAMMATION IN THE LUNG
Document Type and Number:
Japanese Patent JP2023016835
Kind Code:
A
Abstract:
To provide a method for modulating inflammasome activity and inflammation in the lungs.SOLUTION: The present invention provides compositions and methods for reducing inflammation in the lungs of a mammal that is afflicted by a condition that leads to inflammation in the lungs. The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s).SELECTED DRAWING: None
Inventors:
Keene, robert
Dietrich, Dalton
Car, nadine
Woo, shoe
De Libero Vaccari, Juan Pablo
Dietrich, Dalton
Car, nadine
Woo, shoe
De Libero Vaccari, Juan Pablo
Application Number:
JP2022181180A
Publication Date:
February 02, 2023
Filing Date:
November 11, 2022
Export Citation:
Assignee:
University of Miami
International Classes:
A61K45/00; A61K31/727; A61K39/395; A61P11/00; A61P11/06; A61P17/02; A61P25/00; A61P25/16; A61P29/00; A61P35/00; A61P37/00; A61P37/06
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
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