Title:
被験物の安全性予測方法、化粧品の製造方法、安全性予測用の高安全性範囲及び／又は低安全性範囲の特定方法、および安全性予測用媒体
Document Type and Number:
Japanese Patent JP7302033
Kind Code:
B2
Abstract:
Provided is a safety prediction method which can predict the safety of a test object, while not depending on an animal experiment or while suppressing dependency on the animal experiment. The present invention addresses a test object safety prediction method for predicting the safety of a test object in a prescribed safety test. The method according to the present invention: considers, as a high safety object, a reference having high safety pertaining to a prescribed safety test among a plurality of types of references, and, as a low safety object, a reference having low safety; and predicts the safety of the test object on the basis of whether a parameter of a Hansen solubility parameter (HSP) value of the test object is included in a high safety range and/or a low safety range that are/is specified on the basis of at least one parameter of HSP values of the respective references.
Inventors:
Ren Ito
Hideki Yamamoto
Koji Toyoda
Yuki Sakurai
Hideki Yamamoto
Koji Toyoda
Yuki Sakurai
Application Number:
JP2021572616A
Publication Date:
July 03, 2023
Filing Date:
April 14, 2021
Export Citation:
Assignee:
Milbon Co., Ltd.
Kansai University
Kansai University
International Classes:
G01N33/15; A61K8/00; A61Q1/00; A61Q19/00
Domestic Patent References:
| JP2016185129A | ||||
| JP2014211442A | ||||
| JP2018173336A |
Other References:
NAKAMURA DAISUKE、外2名,Nontoxic organic solvents identified using an a priori approach with Hansen solubility parameters,Chemical Communications,2017年,Vol.53,No.29 , Page.4096-4099
山本博志,溶解度パラメータの計算方法と、溶解性評価への利用,Material Stage,日本,2009年,Vol.9, No.5,pp.21-23
山本博志,溶解度パラメータの計算方法と、溶解性評価への利用,Material Stage,日本,2009年,Vol.9, No.5,pp.21-23
Attorney, Agent or Firm:
Hidetada Kato
Yusuke Aji
Yusuke Aji