Title:
METHOD OF PREPARATION OF FORMULATION OF PEPTIDE ANGIOTENSIN-(1-7) AND ANALOG, AGONIST, AND ANTAGONIST THEREOF, USING CYCLODEXTRIN, LIPOSOME AND BIODEGRADABLE POLYMER, AND/OR THEIR MIXTURE AND PRODUCT
Document Type and Number:
Japanese Patent JP2011037868
Kind Code:
A
Abstract:
To provide a medical preparation for the research or treatment of arterial hypertension of warm-blooded animals and other cardiovascular disorder and its concomitant disease, wound, burn wound, actinic erythema, tumor, diabetes, mobility of sperm, nephropathia, gastrointestinal and gynecological disorder, neoangiogenesis, vascular formation, alopecia and blood disorder or for the research of G protein conjugated receptor MAS as a ligand.
The present invention provides the medical preparation of D-Ala7-angiotensin-(1-7)(A-779) and its analogs and derivatives, D-Pro7-angiotensin-(1-7) and its analogs or derivatives, and Ang-(1-7) analogs or derivatives using hydrophilic cyclodextrin, liposome, a biodegradable polymer and its derivatives.
Inventors:
MILLAN RUBEN DARIO SINISTERRA
DOS SANTOS ROBSON AUGUSTO SOUZA
FREZAD FREDERIC JEAN GEORGE
NADU ANA PAULA
DOS SANTOS ROBSON AUGUSTO SOUZA
FREZAD FREDERIC JEAN GEORGE
NADU ANA PAULA
Application Number:
JP2010215646A
Publication Date:
February 24, 2011
Filing Date:
September 27, 2010
Export Citation:
Assignee:
UNIV MINAS GERAIS
International Classes:
A61K38/22; A61K9/127; A61K9/16; A61K9/50; A61K38/08; A61K38/46; A61K45/00; A61K47/04; A61K47/08; A61K47/10; A61K47/12; A61K47/14; A61K47/24; A61K47/26; A61K47/28; A61K47/30; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/40; A61K47/44; A61K47/48; A61P1/00; A61P3/10; A61P7/00; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P15/00; A61P17/02; A61P17/14; A61P27/02; A61P35/00
Domestic Patent References:
| JP2005511577A | 2005-04-28 | |||
| JP2002542201A | 2002-12-10 | |||
| JPH07241457A | 1995-09-19 | |||
| JPH06211666A | 1994-08-02 | |||
| JPH11500404A | 1999-01-12 | |||
| JPH09216810A | 1997-08-19 | |||
| JP2001503802A | 2001-03-21 |
Foreign References:
| WO2001030320A1 | 2001-05-03 |
Other References:
JPN6008063729; ＲＥＧＵＬＡＴＯＲＹ ＰＥＰＴＩＤＥＳ ＶＯＬ．９１, 2000, Ｐ．４５-６２
JPN6008063731; ＣＨＥＭＴＲＡＣＴＳ ＯＲＧ ＣＨＥＭ ＶＯＬ．２， ＮＯ．４, 1989, Ｐ．２４３-２４４
JPN6008063731; ＣＨＥＭＴＲＡＣＴＳ ＯＲＧ ＣＨＥＭ ＶＯＬ．２， ＮＯ．４, 1989, Ｐ．２４３-２４４
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
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