To provide a method of synthesizing an aromatic compound derivative with ease and at a low cost in a short step and with good selectivity by using a compound capable of being derived from phenols.
The method of preparing a compound represented by formula (I) (wherein X is a substituent; R1 is an electron-attracting substituent having a Hammett σp constant of >0; m is an integer of 1-5; R2 is a substituent; n is an integer of 0-4; and a plurality of R1s, a plurality of R2s or R1 and R2 may be linked among themselves or with each other to form a ring) comprises reacting a compound represented by formula (II) (wherein R3 and R4 are each an alkyl group, an aryl group or a heterocyclic group, and R3 and R4 may be linked with each other to form a ring; and R1, R2, m, and n are the same as defined above) with a nucleophilic agent (I).
TAKEUCHI KIYOSHI
