7α-(ζ-アルキルアミノ-ω-ペルフルオロアルキル)アルキル側鎖を有するエストロゲン-拮抗性11β-フルオロ-17α-アルキルエストラ-1,3,5(10)-トリエン-3,17-ジオールの調製方法、及びα-アルキル(アミノ)-ω-ペルフルオロ(アルキル)アルカン類及びそれらの調製方法

Title:

Document Type and Number:

Japanese Patent JP2010536910

Kind Code:

A

Abstract:

The present invention relates to a new process for preparing estrogen-antagonistic 11²-fluoro-17±-alkylestra-1,3,5(10)-triene-3,17-diols of the general formula I having a 7±-(¾-alkylamino-É-perfluoroalkyl)alkyl side chain and to ±-alkyl(amino)-É-perfluoro(alkyl)alkanes of the general formula II, to processes for their preparation and to the intermediates required for this purpose.

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Inventors:

Michael, Zander
Grossbach, Dunya
Christian, Dinter
Hasfeld, Jorma
Voig Trainer, David

Application Number:

JP2010522266A

Publication Date:

December 02, 2010

Filing Date:

August 28, 2008

Export Citation:

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Assignee:

Bayer Schering Pharma Aktiengesellschaft

International Classes:

C07C209/70; C07C21/18; C07C33/42; C07C211/15; C07C211/24; C07C211/27; C07C309/66; C07C309/73; C07F9/54; C07J1/00; C07B61/00

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima

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