Title:
置換オクタノイルアミドの調製方法
Document Type and Number:
Japanese Patent JP4853888
Kind Code:
B2
Abstract:
Compounds of formula (XII), are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is reacted with an amine to form a carboxamide, the halogen is replaced with azide, if necessary after the introduction of a hydroxy protecting group, the resulting azide is converted to a lactone, the lactone is amidated and then the azide converted to the amine group, in order to obtain compounds of formula (I) or a salt thereof.
Inventors:
Herolt, peter
Stutz, Stephan
Stutz, Stephan
Application Number:
JP2002514081A
Publication Date:
January 11, 2012
Filing Date:
June 26, 2001
Export Citation:
Assignee:
Novartis Pharma AG
International Classes:
C07C231/12; C07D307/33; A61K31/165; A61P9/12; C07B53/00; C07C231/02; C07C235/34; C07C247/12; C07B61/00; C07C237/20
Domestic Patent References:
| JPH0853434A | 1996-02-27 | |||
| JPH0881430A | 1996-03-26 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fusayuki Saito
Satoko Ito
Keiko Ozawa
Fumio Shinoda
Fusayuki Saito
Satoko Ito
Keiko Ozawa
Fumio Shinoda