Title:
METHOD FOR PRODUCING (1R,2S)-1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID ESTER
Document Type and Number:
Japanese Patent JP2013173677
Kind Code:
A
Abstract:
To provide a method for inexpensively and efficiently producing a (1R,2S)-1-amino-2-vinyl cyclopropane carboxylic acid ester, which is useful as a pharmaceutical intermediate.
A (1R,2S)-1-amino-2-vinyl cyclopropane carboxylic acid ester derivative having improved optical purity is produced by forming a salt from an optically active carboxylic acid and a 1-amino-2-vinyl cyclopropane carboxylic acid ester in a racemic form or having a low optical purity, and precipitating the salt in a solid form from a solvent.
Inventors:
TANAKA TATSUYOSHI
NISHIYAMA AKIRA
NISHIYAMA AKIRA
Application Number:
JP2010136377A
Publication Date:
September 05, 2013
Filing Date:
June 15, 2010
Export Citation:
Assignee:
KANEKA CORP
International Classes:
C07B57/00; C07C227/42; C07C229/48