METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID

Title:

METHOD FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID

Document Type and Number:

Japanese Patent JP2010035554

Kind Code:

A

Abstract:

To provide a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid at high yield and high selectivity.

There is provided the method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid through hydrolyzing a (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester using an esterase originating from Burkholderia cepacia.

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Inventors:

HATAKEYAMA KEISUKE
MIKI TAKASHI
HIRATA NORIHIKO

Application Number:

JP2009161114A

Publication Date:

February 18, 2010

Filing Date:

July 07, 2009

Export Citation:

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Assignee:

SUMITOMO CHEMICAL CO
DAIICHI SANKYO CO LTD

International Classes:

C12P41/00; C07C51/09; C07C61/15; C07C67/347; C07C69/74; C07B61/00

Domestic Patent References:

JP2004217608A	2004-08-05
JPH09124556A	1997-05-13
JP2001000176A	2001-01-09

Foreign References:

WO1998010091A1

1998-03-12

Attorney, Agent or Firm:

Patent Business Corporation Saegusa International Patent Office

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