Title:
HMG-COAレダクターゼ阻害性メバロン酸誘導体の製造方法
Document Type and Number:
Japanese Patent JP2005520818
Kind Code:
A
Abstract:
The invention relates to a process for the manufacture of a compound of formula: (Formula I); or a salt, especially a pharmaceutically acceptable salt with a base, thereof or a lactone thereof wherein the element (a) represents -CH2-CH2 CH- or -CH-CH- and R represents a cyclic radical.
Inventors:
Gottfried Zedermeier
Christian mates
Christian mates
Application Number:
JP2003569624A
Publication Date:
July 14, 2005
Filing Date:
February 20, 2003
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D215/14; A61K31/404; A61K31/47; A61P3/06; A61P9/10; A61P43/00; C07C27/02; C07C51/09; C07C59/11; C07C59/42; C07C59/46; C07C59/48; C07C67/31; C07C69/732; C07C311/01; C07D209/24; C07D309/30; C07F9/50; C07F9/535; C07F15/00; C07F15/02; C07F15/04; C07F15/06; (IPC1-7): C07D209/24; A61P3/06; A61P9/10; A61P43/00; C07C27/02; C07C51/09; C07C59/11; C07C59/46; C07C59/48; C07C67/31; C07C69/732; C07C311/01; C07D215/14; C07F9/50
Domestic Patent References:
| JP2001261689A | 2001-09-26 | |||
| JP2001270865A | 2001-10-02 | |||
| JPH11335385A | 1999-12-07 | |||
| JPH11236345A | 1999-08-31 | |||
| JP2001104795A | 2001-04-17 | |||
| JP2000327659A | 2000-11-28 | |||
| JP2000256234A | 2000-09-19 | |||
| JP2000212110A | 2000-08-02 | |||
| JPH11322649A | 1999-11-24 | |||
| JPH10236986A | 1998-09-08 |
Foreign References:
| WO2001092223A1 | 2001-12-06 | |||
| WO1997020789A1 | 1997-06-12 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima