Title:
Ｔ細胞又はＮＫ細胞の製造方法、Ｔ細胞又はＮＫ細胞の培養用培地、Ｔ細胞又はＮＫ細胞の培養方法、未分化Ｔ細胞の未分化状態を維持する方法及びＴ細胞又はＮＫ細胞の増殖促進剤
Document Type and Number:
Japanese Patent JP7016102
Kind Code:
B2
Abstract:
An object of the present invention is to provide a method for producing T cells or NK cells, a culture medium for culturing T cells or NK cells, a method for culturing T cells or NK cells, a method for maintaining the undifferentiated state of undifferentiated T cells, and a growth promoter for T cells or NK cells, which are capable of efficiently proliferating T cells or NK cells and maintaining the state of the cells (for example, undifferentiated property).The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a bisbenzylisoquinoline alkaloid represented by formula (X-1) or formula (X-2) or a compound resulting from cleavage of one ether bond thereof or a pharmaceutically acceptable salt thereof, and the like.
Inventors:
Shinichiro Takayanagi
Atsushi Kunisato
Nakaganji Fuka
Ken Fukumoto
Kazuki Nakazono
Kaneko Shin
Yohei Kawai
Atsushi Kunisato
Nakaganji Fuka
Ken Fukumoto
Kazuki Nakazono
Kaneko Shin
Yohei Kawai
Application Number:
JP2020560042A
Publication Date:
February 04, 2022
Filing Date:
December 06, 2019
Export Citation:
Assignee:
Kirin Holdings Company, Limited
Kyoto University
Kyoto University
International Classes:
C12N5/0783
Other References:
Eur. J. Pharmacol.,1999年,Vol. 367,p. 389-398
Attorney, Agent or Firm:
Patent business corporation glory patent office