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Title:
METHOD FOR PRODUCING ARYL CARBAPENEM COMPOUND
Document Type and Number:
Japanese Patent JP2007039383
Kind Code:
A
Abstract:

To provide methods for industrially producing a carbapenem medicament having high antibacterial activity, high in safety and also high in peroral absorbability, and intermediates for the medicament, respectively.

The method for producing the objective carbapenem compound comprises reacting an aryl glyoxalate compound with a 2-azetidinone derivative followed by conducting halogenation, phosphidation and then deprotection.


Inventors:
SUNAKAWA JUN
OGAWA TAKANORI
SASAKI MIKIO
Application Number:
JP2005225610A
Publication Date:
February 15, 2007
Filing Date:
August 03, 2005
Export Citation:
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Assignee:
DAINIPPON SUMITOMO PHARMA CO
International Classes:
C07D477/00; A61K31/407; A61P31/04; A61P43/00; C07D205/08; C07F9/568; C07B53/00
Domestic Patent References:
JPH11504912A1999-05-11
JPH10507185A1998-07-14
JPH09504285A1997-04-28
JP2005170880A2005-06-30
Foreign References:
WO2003040146A12003-05-15
WO2002053566A12002-07-11
WO2003089431A12003-10-30
US5356889A1994-10-18
Attorney, Agent or Firm:
Yobe



 
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