Title:
フェニルエタノールアミンの結晶形の製造方法
Document Type and Number:
Japanese Patent JP4799592
Kind Code:
B2
Abstract:
The subject-matter of the invention is the B form of ethyl [(7S)-7-[(2R)-2-(3-chlorophenyl)-2-hydroxyethylamino]-5,6,7,8-tetrahydronaphth-2-yloxy]acetate hydrochloride, of use as a medicament, which exhibits in particular the following physical characteristics: characteristic IR absorption peaks (cm-1): 2780, 2736, 1722, 1211; melting point: 129+/-2° C.; characteristic lines of the powder X-ray diffraction diagram (to within 0.1(2theta)): 7.69, 9.83, 13.95, 16.58, 18.70, 20.40, 21.57, 23.40, 24.15 and 25.64. The product can be obtained by salification of the base or recrystallization of the salt from an alcohol.
Inventors:
Karon, Antoine
Monnier, Olivier
Ober, Sabrina
Roche, Jerome
Jiri, Isabel
Monnier, Olivier
Ober, Sabrina
Roche, Jerome
Jiri, Isabel
Application Number:
JP2008178049A
Publication Date:
October 26, 2011
Filing Date:
July 08, 2008
Export Citation:
Assignee:
Sanofi-Aventis
International Classes:
A61P1/00; A61K31/216; C07C213/10; A61K31/24; A61P25/24; C07C217/74; C07C219/26; C07C227/18; C07C229/50
Domestic Patent References:
| JP2004530725A | ||||
| JP64066152A | ||||
| JP5025040A |
Attorney, Agent or Firm:
Shintaro Nogawa