Title:
ジフルオロメチル基含有アルコ−ル類の製造方法
Document Type and Number:
Japanese Patent JP6462426
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a simple production method for introducing a difluoromethyl group and a hydroxy group to an olefin in one step.SOLUTION: A method of obtaining a difluoromethyl group-containing alcohol represented by formula (2) comprises reacting an olefin of general formula R2R3=CHR1 with a difluoromethylating agent in a water-organic solvent mixed solvent in the presence of a tris(2-phenylpyridine)iridium (III) catalyst by visible-light irradiation. (R1 and R3 are each H or an alkyl group such as a methyl or ethyl group, and R2 is a cyclohexyl group or substituted/unsubstituted phenyl group.)SELECTED DRAWING: None
Inventors:
Takashi Koike
Arai Yusuke
Munetaka Aida
Arai Yusuke
Munetaka Aida
Application Number:
JP2015045831A
Publication Date:
January 30, 2019
Filing Date:
March 09, 2015
Export Citation:
Assignee:
National University Corporation Tokyo Institute of Technology
Tosoh Finechem Co., Ltd.
Tosoh Finechem Co., Ltd.
International Classes:
B01J31/12; C07C29/64; B01J35/02; C07C31/44; C07C33/46; C07C67/31; C07C69/732
Other References:
YASU, Y. et al.,Angewandte Chemie, International Edition,2012年,Vol. 51,pp. 9567-9571
YASU, Y. et al.,59th Symposium on Organometallic Chemistry, Japan,2012年,Vol. 59,p. 183,P3A-34
TANG, X.-J. et al.,Organic Letters,2014年,Vol. 16,pp. 4594-4597
TANG, X.-J. et al.,Angewandte Chemie International Edition,2015年 2月18日,Vol. 54,pp. 4246-4249
YASU, Y. et al.,59th Symposium on Organometallic Chemistry, Japan,2012年,Vol. 59,p. 183,P3A-34
TANG, X.-J. et al.,Organic Letters,2014年,Vol. 16,pp. 4594-4597
TANG, X.-J. et al.,Angewandte Chemie International Edition,2015年 2月18日,Vol. 54,pp. 4246-4249
Attorney, Agent or Firm:
Koji Nagato