Title:
ジホスフィン化合物の製造法およびその製造中間体
Document Type and Number:
Japanese Patent JP5043883
Kind Code:
B2
Abstract:
A production method of a_compound represented by the formula wherein R<1a>, R<1b>, R<1c>, R<1d>, R<1e>, R<1f>, R<2a>, R<2b>, R<2c> R<2d>, R<2e> and R<2f> are the same or different and each is a hydrogen atom and the like, and R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9> and R<10> are the same or different and each is a hydrogen atom and the like, or a salt thereof, which comprises reacting a compound represented by the formula wherein X is a leaving group and other symbols are as defined above, or a salt thereof, with a phosphine-borane complex represented by the formula wherein the symbols are as defined above, or a salt thereof, in a solvent in the presence of an amine and a nickel catalyst, is provided.
Inventors:
Mitsutaka Goto
Mitsuhisa Yamano
Mitsuhisa Yamano
Application Number:
JP2009096377A
Publication Date:
October 10, 2012
Filing Date:
April 10, 2009
Export Citation:
Assignee:
Takeda GmbH
International Classes:
C07F9/50; C07F5/02; C07F9/46; C07F9/655; C07F19/00
Domestic Patent References:
| JP2003206295A |
Other References:
Lee et al.,Angewandte Chemie International Edition,2002年 3月 7日,Vol. 41,p. 847-849
McKinstry et al.,An Efficient Procedure for the Synthesis of C-Chiral Bisphosphines,Tetrahedron,1995年,Vol.51, no.28,P.7655-7666
今本恒雄,ホスフィンボランの合成と反応,有機合成化学協会誌,1993年,第51巻第3号,223-231頁
McKinstry et al.,An Efficient Procedure for the Synthesis of C-Chiral Bisphosphines,Tetrahedron,1995年,Vol.51, no.28,P.7655-7666
今本恒雄,ホスフィンボランの合成と反応,有機合成化学協会誌,1993年,第51巻第3号,223-231頁
Attorney, Agent or Firm:
Takashima Ichi