To provide a method for separating a microbial community of estrogen-decomposing bacteria, to provide a method for producing a pro-biotic product which diminishes an estrogen- depending tumor risk, an endocrine disruptive risk, etc., by decomposing estrogens widely contained in foods, and to provide a strain of microorganism used for the same.
This method for separating the microbial community of the estrogen- decomposing bacteria comprises enrichingly culturing estriol-utilizing bacteria by adding a microorganism-containing sample which is comparatively highly safe and contains various microorganisms, such as excrement collected from a healthy human body, to a mineral medium in which the estrogen is solely used as a carbon source, separating the enrichingly cultured specific bacteria into a single strain of the bacteria, or consortia of the bacteria, and confirming that the enrichingly cultured bacteria have decomposing activity not only on the estriol but also on 17β-estradiol and estrone and have no pathogenicity. The method for producing the pro-biotic product comprises adding the estorogenic microorganism as it is or an estrogen-decomposing enzyme to foodstuffs, or adding the microorganism or the enzyme to an intestinal ecosystem as an enteric capsule, a suppository, etc., so as to try to diminish an amount of the estrogen in the intestinal ecosystem.
SHIBATA SATORU
MATSUMOTO SATOSHI
MATSUMOTO SATOSHI
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