Title:
METHOD OF PRODUCING GALACTO TYPE TREHALOSE OR DERIVATIVE THEREOF AND LIGAND FOR VERO TOXIN ORIGINATING FROM TREHALOSE OBTAINED USING THE SAME
Document Type and Number:
Japanese Patent JP2003073391
Kind Code:
A
Abstract:
To provide a ligand that can trap the Vero toxin by changing the chemical structure of inexpensive trehalose.
Trehalose, a disaccharide from tow glucoses, is used as a starting substance and the hydroxy group in the 4-position in one glucose is inverted to the axial conformation to introduce the galactose structure whereby the galacto type trehalose or a derivative thereof is produced. The resultant galacto type trehalose or a derivative thereof is introduced into the main chain of a polymer to give the ligand for the Vero toxin.
Inventors:
NISHIDA YOSHIHIRO
DOI HIROSHI
FURUTA YUKI
KOBAYASHI KAZUKIYO
DOI HIROSHI
FURUTA YUKI
KOBAYASHI KAZUKIYO
Application Number:
JP2001265737A
Publication Date:
March 12, 2003
Filing Date:
September 03, 2001
Export Citation:
Assignee:
INST NAGOYA IND SCIENCE RES
International Classes:
C07H3/04; A61K31/785; A61P39/02; C07H15/04; C07H23/00; (IPC1-7): C07H3/04; A61K31/785; A61P39/02; C07H15/04; C07H23/00
Attorney, Agent or Firm:
Michio Nakajima (1 person outside)