Title:
ステロイド誘導体のケタールの製造方法
Document Type and Number:
Japanese Patent JP3984315
Kind Code:
B2
Abstract:
The invention relates to a method of the preparation of a steroid derivative ketal according to the general formula I: wherein R1 is CH3 or C2H5; R2 is OH; R3 is H, CH3; C IDENTICAL CH, CH2Hal,, or CH2CN; or R2 and R3 together are O; R4 is (2-5C) alkylene; and Hal is Cl, Br or I, characterized in that the compound of formula II: wherein R1, R2 and R3 have the previously given meanings, is treated in the presence of an orthoester of formula III: or an orthoester of formula IV: wherein R4 has the previously indicated meaningor a mixture thereof with an alcohol according to the general formula HOR4OH, wherein R4 has the previously given meaning.
Inventors:
Franciscus Theodorus Leonardus Brands
Pieter Freyhoff
Pieter Freyhoff
Application Number:
JP32007996A
Publication Date:
October 03, 2007
Filing Date:
November 29, 1996
Export Citation:
Assignee:
Narmrose Fuennault Chap Organon
International Classes:
C07J1/00; C07J41/00; C07J21/00; C07J75/00
Domestic Patent References:
| JP9501172A | ||||
| JP62153297A |
Other References:
J. Prakt. Chem.,1995年,Vol.337,p.358-362
Steroids,1982年,Vol.39, No.6,p.607-615
Pharmazie,1978年,Vol.33, No.12,p.792-798
Pharmazie,1984年,Vol.39, No.7,p.496-497
Agric. Biol. Chem.,1983年,Vol.47, No.1,p.89-95
Steroids,1982年,Vol.39, No.6,p.607-615
Pharmazie,1978年,Vol.33, No.12,p.792-798
Pharmazie,1984年,Vol.39, No.7,p.496-497
Agric. Biol. Chem.,1983年,Vol.47, No.1,p.89-95
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura