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Title:
METHOD FOR PRODUCING N-[1-(S)-ETHOXYCARBONYL-3- PHENYLPROPYL]-L-ALANINE N-CARBOXYANHYDRIDE
Document Type and Number:
Japanese Patent JP2002179658
Kind Code:
A
Abstract:

To provide both a method for producing the subject NEPA-NCA without using poisonous phosgene, diphosgene or triphosgene and a method for industrially producing the NEPA-NCA by which an operation can be economically, safely and simply carried out.

The methods for producing N-[1-(S)-ethoxycarbonyl-3- phenylpropyl]-L-alanine N-carboxyanhydride represented by formula (I) comprise reacting a compound represented by formula (IV) (R is a 1-6C alkyl group) with an acyl group activation reagent and then bringing the resultant substance into contact with water.


Inventors:
CHEN CHONG-MING
LIU YU-LIANG
CHAO YA-CHIEH
WU CHIEN-HUANG
Application Number:
JP2001000311921
Publication Date:
June 26, 2002
Filing Date:
October 09, 2001
Export Citation:
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Assignee:
EVERLIGHT USA INC
International Classes:
C07C269/04; C07C271/22; C07D263/44; (IPC1-7): C07D263/44; C07C269/04; C07C271/22
Attorney, Agent or Firm:
塩澤 寿夫 (外2名)