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Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE 4-AMINO-3-SUBSTITUTED PHENYLBUTANOIC ACID
Document Type and Number:
Japanese Patent JP2010001235
Kind Code:
A
Abstract:

To provide a method for producing an optically active 4-amino-3-substituted phenylbutanoic acid, by which the optically active 4-amino-3-substituted phenylbutanoic acid having a sufficient purity can be produced in simpler operations than conventional operations.

Provided is the method for producing the optically active 4-amino-3-substituted phenylbutanoic acid, including a process for purifying the optically active 4-amino-3-substituted phenylbutanoic acid in an aqueous organic acid solution. The organic acid is preferably acetic acid, and the concentration of the aqueous organic acid solution is preferably 0.2-3%. Further, the optically active 4-amino-3-substituted phenylbutanoic acid is preferably (R)-4-amino-3-(4-chlorophenyl)butanoic acid or (S)-4-amino-3-(4-chlorophenyl)butanoic acid.


Inventors:
MURAKAMI KAZUO
TAKEDA MASAO
KATO YOJI
Application Number:
JP2008160314A
Publication Date:
January 07, 2010
Filing Date:
June 19, 2008
Export Citation:
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Assignee:
SUMITOMO CHEMICAL CO
International Classes:
C07C227/42; C07C229/34; C07B57/00
Domestic Patent References:
JP2005518338A2005-06-23
JPS6051154A1985-03-22
JP2007332129A2007-12-27
JPH06306029A1994-11-01
JPH04266864A1992-09-22
JPS6357560A1988-03-12
JPS6032752A1985-02-19
JPS61501704A1986-08-14
JP2005518338A2005-06-23
JPS6051154A1985-03-22
Foreign References:
DD212508A11984-08-15
WO2007096314A22007-08-30
DD212508A11984-08-15
WO2007096314A22007-08-30
Attorney, Agent or Firm:
Kuro Fukami
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Hisato Noda
Masayuki Sakai
Nobuo Arakawa



 
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