Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE NIPECOTAMIDE
Document Type and Number:
Japanese Patent JP2011042647
Kind Code:
A
Abstract:
To provide a method for the producing optically active nipecotamide by an advantageous process on a commercial scale.
The method for producing optically active nipecotamide includes the steps of: reacting nipecotamide with optically active lactic acid in a solvent to prepare a diastereomer salt mixture and causing one of diastereomer salts contained in the diastereomer salt mixture to precipitate; collecting the precipitated diastereomer salt; and treating the collected diastereomer salt with a base to cause optically active nipecotamide to release.
Inventors:
WATANABE YOSUKE
OTANI YUTAKA
OTANI YUTAKA
Application Number:
JP2010162672A
Publication Date:
March 03, 2011
Filing Date:
July 20, 2010
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO
International Classes:
C07D211/60; C07B57/00
Domestic Patent References:
| JPH09143128A | 1997-06-03 | |||
| JPH07258175A | 1995-10-09 | |||
| JPH06256227A | 1994-09-13 |
Foreign References:
| WO2008102720A1 | 2008-08-28 |
Other References:
JPN6014031708; 新実験化学講座１基本操作Ｉ , 1975, ３２６-３２７
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki