Title:
METHOD FOR PRODUCING POLYAMIDE USING CADAVERINE FERMENTATION CORYNEFORM BACTERIUM
Document Type and Number:
Japanese Patent JP2009284905
Kind Code:
A
Abstract:
To enable cadaverine fermentation with a coryneform bacterium by using a genetic engineering technique, to carry out the cadaverine fermentation with a recombinant coryneform bacterium, and to isolate high-purity cadaverine from a fermentation liquid thereof.
The problems are solved by culturing a coryneform bacterium having an L-lysine decarboxylase activity, and at least either homoserine auxotrophy or S-(2-aminoethyl)-L-cysteine resistance, suitably combining concentration, addition of an organic solvent, filtration, crystallization, extraction, distillation etc., thereby producing cadaverine, cadaverine dihydrochloride or a cadaverine dicarboxylate from the culture solution.
Inventors:
MIMIZUKA TAKASHI
HATAHIRA TOMOKO
SAWAI HIDEKI
YAMADA MASANARI
KATO KIMIYA
HATAHIRA TOMOKO
SAWAI HIDEKI
YAMADA MASANARI
KATO KIMIYA
Application Number:
JP2009152122A
Publication Date:
December 10, 2009
Filing Date:
June 26, 2009
Export Citation:
Assignee:
TORAY INDUSTRIES
International Classes:
C12N1/21; C07C55/14; C07C211/09; C12N15/09; C12P13/00
Domestic Patent References:
| JP2002223770A | 2002-08-13 |
Foreign References:
| WO1995023864A1 | 1995-09-08 | |||
| WO2000063388A1 | 2000-10-26 |
Other References:
JPN6011058368; Ｔｅｔｒａｈｅｄｒｏｎ ｌｅｔｔ．， ３０［１８］（１９８９） ｐ．２３３７-２３４０
JPN6009021733; Ｍａｃｒｏｍｏｌｅｃｕｌｅｓ ｖｏｌ．２９， ｎｏ．１６, 1996, ｐ．５４０６-５４１５
JPN6009021733; Ｍａｃｒｏｍｏｌｅｃｕｌｅｓ ｖｏｌ．２９， ｎｏ．１６, 1996, ｐ．５４０６-５４１５