METHOD FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYL)HEXANOIC ACID

Title:

METHOD FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYL)HEXANOIC ACID

Document Type and Number:

Japanese Patent JP2003137835

Kind Code:

A

Abstract:

To provide a method for producing (R)-3-hydroxy-3-(2-phenylethyl) hexanoic acid, by which the (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid useful as a medicine raw material can efficiently be produced from racemic 3- hydroxy-3-(2-phenylethyl)-hexanoic acid in a high optical purity and in a relative ly high yield.

This method for producing the (R)-3-hydroxy-3-(2-phenylethyl) hexanoic acid is characterized by optically resolving the racemic 3-hydroxy-3-(2- phenylethyl)hexanoic acid with (R)-N-para-hydroxybenzyl-α-phenyl-β-para- tolyethylamine.

Inventors:

TANAKA MASAHIDE
MATSUI KOZO
ITAYA NOBUSHIGE

Application Number:

JP2001333291A

Publication Date:

May 14, 2003

Filing Date:

October 30, 2001

Export Citation:

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Assignee:

SUMIKA FINE CHEMICALS CO LTD

International Classes:

C07C51/487; C07B57/00; C07C59/13; (IPC1-7): C07C51/487; C07C59/13

Attorney, Agent or Firm:

Takashima Hajime

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