METHOD FOR PRODUCING STEROID COMPOUND

Title:

METHOD FOR PRODUCING STEROID COMPOUND

Document Type and Number:

Japanese Patent JP2007210888

Kind Code:

A

Abstract:

To provide a new method for producing a steroid compound.

The present invention provides a method for producing 5β-3,7-dioxocholanic acid or its ester derivative by passing through the following four steps (I) to (IV) by using cholesta-5,7,24-trien-3β-ol or ergosta-5,7,24(28)-trien-3β-ol, desmosterol or fucosterol, ergosta-5,24(28)-diene-3β-ol which are sterols having double bonds at 5 position and 24 position as a raw material: (I) a step for carrying out oxidation of hydroxy group at 3 position and isomerization of double bond at 5 position to 4 position, (II) a step for introducing a carboxyl group or its ester derivative to a site at 24 position by oxidative cleavage of side chain, (III) a step for introducing an oxygen functional group to a site at 7 position and (IV) a step for carrying out 5β three-dimensional construction by reductive saturation of double bond at 4 position.

Inventors:

TAKEHARA JUN
KAWAI JUNYA
FUJIWARA NAOYA
ENDO KYOKO
HOSOKAWA AKIYOSHI
SUMIYA NAOKO

Application Number:

JP2006010233A

Publication Date:

August 23, 2007

Filing Date:

January 18, 2006

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MITSUBISHI CHEM CORP

International Classes:

C07J9/00; C07J17/00; C07J41/00; C07J71/00

Attorney, Agent or Firm:

Patent Service Corporation Patent Office Sykes

Previous Patent: RING-FUSED BICYCLIC PYRIMIDINE DERIVATIVE

Next Patent: METHOD FOR MONOMERIZING STEREOCOMPLEX TYPE POLYLACTIC ACID