糖鎖の製造方法 - National University Corporation Tottori University

Title:

糖鎖の製造方法

Document Type and Number:

Japanese Patent JP7417930

Kind Code:

B2

Abstract:

To provide methods for producing carbohydrate chains with shortened reaction time by successively conducting glycosylation of reaction intermediates and sugar receptors without waiting accumulation of the activated reaction intermediates.SOLUTION: Disclosed is a method for producing a carbohydrate chain comprising: selecting one hexose represented by formula (1); activating the hexose to generate an intermediate cation having dissociated -X site represented by formula (2) or an equivalent thereof; and simultaneously linking the cationic site of the intermediate cation of formula (2) to a hydroxy moiety of a hexose of the same kind represented by formula (1). In the formula, R1, R2, R3 and X are specific substituents. One of the two R1 is hydroxy.SELECTED DRAWING: Figure 1

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Inventors:

Toshiki Nogami
Tomoaki Hamada
Kei Sakai

Application Number:

JP2020020679A

Publication Date:

January 19, 2024

Filing Date:

February 10, 2020

Export Citation:

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Assignee:

National University Corporation Tottori University
Koganei Co., Ltd.

International Classes:

C07H15/203; C08B13/00

Domestic Patent References:

JP2017165725A

Other References:

Org. Lett.,2015年,17,1525-1528
Org. Lett.,2013年,15,4520-4523
Org. Lett.,2011年,13,1544-1547

Attorney, Agent or Firm:

Sykes Patent Attorney Corporation

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